These are my brief observations of the impact from the new GW Boss cards:
1. Use of Ceto/Charybdis in Solomon is now obsolete.
2. Solomon difficult now requires ~3 mins to complete using dual Anauel compared to the 5-6 mins previously needed with an attack team. Solomon Insane also just got a lot more feasible and quicker at ~6 mins. Guild Lv40 will be much more achievable. A lot of people will have an easier time leveling to LV170+. Energy potions now burn a lot faster during weekends.
3. 8* Dragons are now everyone's dream cards. Skilled 8* Dragons are now king of cards. You can also slot in panzers for more HP if you have the CP like this.
4. Previous stages that used to require revives now require none or less revives.
5. Everyone will again have interest in dragons and level/skill them now. Dragons have regained their value.
6. Panzers just became a hindrance in such team due to it's highly inefficient use of CP costs.
7. Lower level players don't need HP cards to do Solomon difficult anymore, now they need friends with Dragon Queens. Requirements to do Solomon Difficult just got a lot lower.
EDIT:
Thank you Playmage for this awesome addition to the game.
EDIT 2:
To anyone who missed this chance for Anauel, do take note if the next GW Boss is another Dragon Queen then it is extremely likely for that card to have the same awesome leader skill Anauel has. So get prepared to do 50K next war. This is purely hypothetical, I do not guarantee it will have the same effect but it is worth a try.
EDIT 3:
Just found out that it is possible to die using dual Anauel setup. If you cannot afford to lose, please consider a Holy Priestess+Anauel setup instead.